mercoledì 11 marzo 2015

Antidepressant use during pregnancy unlikely to increase risk of asthma in offspring

Antidepressant use during pregnancy unlikely to increase risk of asthma in offspring



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A recent study investigated whether use of prenatal antidepressants raised the risk of asthma in the offspring. The cohort study identified more than 733,600 children born in Denmark between 1996 and 2007.
A recent study investigated whether use of prenatal antidepressants raised the risk of asthma in the offspring. The cohort study identified more than 733,600 children born in Denmark between 1996 and 2007. Of that number, 84,683 children were diagnosed with asthma, and 21,371 were exposed to prenatal maternal depression (with a diagnosis of depressive order or use of antidepressants 1 year before or during pregnancy). Nearly 8,900 children were exposed to antidepressants in utero. The hazard ratio (HR) for asthma after any antidepressant use during pregnancy was 1.00, compared with children born to mothers with prenatal depression and no antidepressant use during pregnancy. The researchers determined that the HR after use of selective serotonin reuptake inhibitors only was 0.95, while the HR after newer antidepressants only was 1.11 and it was 1.26 after older antidepressants only. The findings, the researchers report, indicate that "antidepressant use during pregnancy in general did not increase the risk of asthma in the offspring among women with depression, with the exception of use of older antidepressants."
http://pediatrics.aappublications.org/content/early/2015/03/04/peds.2014-4073.abstract

martedì 10 marzo 2015

lunedì 9 marzo 2015

Condoms are more effective when applied by males

via PUBMED  Ann Epidemiol. 2014 Nov;24(11):868-70. doi: 10.1016/j.annepidem.2014.07.017. Epub 2014 Aug 7.
 
 
 

Condoms are more effective when applied by males: a study of young black males in the United States.

Abstract

PURPOSE:

To determine, among a sample of young black male (YBM), whether female application of male condoms for penile-vaginal intercourse would be associated with higher or lower rates of breakage or slippage. A secondary aim was to investigate if higher rates of breakage or slippage were associated with increased odds of acquiring chlamydia and/or gonorrhea.

METHODS:

A cross-sectional study of 412 YBM, aged 15 to 23 years, was conducted in three US cities located in the Southern United States.

RESULTS:

Among YBM reporting frequent female application of condoms, 43.5% reported one or more instance of breakage or slippage, compared with those reporting less frequent female application (27.2%, P = .003). Among YBM reporting one or more event of breakage or slippage, 25.4% tested positive for chlamydia and/or gonorrhea. In contrast, among those not reporting breakage or slippage, 17.2% tested positive (P = .047).

CONCLUSIONS:

Findings suggest that educational and behavioral interventions should seek to improve young women's skills relative to condom application and use. Further studies could also investigate whether intervention efforts should encourage some YBM to be responsible for their own condom application.
Copyright © 2014 Elsevier Inc. All rights reserved.

KEYWORDS:

Condoms; Sexual behavior; Sexually transmitted diseases; Young men
PMID:
25193014
[PubMed - in process]

sabato 7 marzo 2015

Laser-assisted liposuction and abdominoplasty

via Pubmed

Aesthetic Plast Surg. 2014 Feb;38(1):49-56. doi: 10.1007/s00266-013-0242-x. Epub 2013 Dec 6.

The effectiveness and safety of combining laser-assisted liposuction and abdominoplasty.

Abstract

BACKGROUND:

Lipoabdominoplasty is nearly a daily aesthetic procedure. Despite the emergence of laser-assisted liposuction, to date, it has not been clearly evaluated combined with abdominoplasty. This prospective study aimed to evaluate the effectiveness and safety of laser-assisted liposuction relative to traditional liposuction combined with high-lateral-tension abdominoplasty.

METHODS:

This study investigated 36 consecutive female patients who underwent high-lateral-tension abdominoplasty combined with liposuction of the upper central abdomen and both flanks. The patients were divided into three equal groups based on the technique used for liposuction. Group 1 underwent conventional liposuction with abdominoplasty. Group 2 underwent a mixture of conventional and laser-assisted liposuction with abdominoplasty. Group 3 underwent laser-assisted liposuction with abdominoplasty.

RESULTS:

The patients in groups 2 and 3 had a better aesthetic outcome than those in group 1 with regard to abdominal contour and skin tightness. No major complications were observed in groups 1 and 2. The patients in group 3 had a higher incidence of complications (3 seromas, 3 central necroses and dehiscence), and one patient underwent secondary sutures.

CONCLUSION:

Laser-assisted liposuction combined with abdominoplasty in the lateral abdomen seems to be a safe technique with good aesthetic outcomes. Although the combined use of laser-assisted liposuction in the lateral and central abdomen can achieve relatively better aesthetic results, it is associated with significant complications, and its use cannot be supported. Proper laser parameters in the central abdominal area still need further study.

LEVEL OF EVIDENCE IV:

This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .